HEALTH BIG DATA
(人工智能健康大數據)

DEEP MIND

NEUSOFT

QUANT TRADING
(人工智能財經大數據)

KENSHO WARREN

BLOOMBERG


PUBLICATIONS

PhD THESIS

BOOK (Appendix Chapters A to D)

  1. Foundations of Soft Case-Based Reasoning, by Sankar K. Pal and Simon C.K. Shiu, John Wiley & Sons, 2004, ISBN: 0-471-08635-5.

AWARD

FUNDING

  • Postdoc Research Scientist Small Project Research Funding, 66,667 HKD, completed with outstanding items, September, 2010.
  • China Medical Board Research Grant, HKU, 62,465 HKD, completed 2015.

PAPER

    Journal paper

  1. Au, T. Y., Yip, R. K., Wynn, S. L., Tan, T.,..., Niu, B.,... & Cheah, K. S.   (2023). Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog – Wnt signaling, causing campomelia. Proceedings of the National Academy of Sciences, 120(1), e2208623119.


  2. Niu, B., Bach, T. N., Chen, X., Chandratre, K. R., Murray, J. I., Zhao, Z., & Zhang, M.   (2022). Computational modeling and analysis of the morphogenetic domain signaling networks regulating C. elegans embryogenesis. Computational and Structural Biotechnology Journal.

    Access to paper website and Software.
    Supplementary movies and figures.


  3. He, L., Sun, Z., Li, J., Zhu, R., Niu, B., Tam, K. L., ... & Chiu, K. (2021). Electrical stimulation at nanoscale topography boosts neural stem cell neurogenesis through the enhancement of autophagy signaling. Biomaterials, 268, 120585.


  4. Babu, R. O., Lui, V. C. H., Chen, Y., Yiu, R. S. W., Ye, Y., Niu, B., ... & Tam, P. K. H. (2020). Beta-amyloid deposition around hepatic bile ducts is a novel pathobiological and diagnostic feature of biliary atresia. Journal of hepatology, 73(6), 1391-1403.


  5. Tan, Z., Kong, M., Wen, S., Tsang, K. Y., Niu, B., Hartmann, C., ... & Cheah, K. S. (2020). IRX3 and IRX5 inhibit adipogenic differentiation of hypertrophic chondrocytes and promote osteogenesis. Journal of Bone and Mineral Research, 35(12), 2444-2457.


  6. Feng, C., Chan, W. C., ..., Niu, B.,..., Cheah K.S.E, ..., Chan, D. (2019). Lgr5 and Col22a1 Mark Progenitor Cells in the Lineage toward Juvenile Articular Chondrocytes. Stem Cell report, Sep 4. pii: S2213-6711(19) 30300-5.


  7. Ali, S.A., Niu, B. (co-first author), Cheah, K.S.E., Alman B.. (2019). Unique and overlapping GLI1 and GLI2 transcrioptional targets in neoplastic chondrocyte. PloS One, 14 (1).

    8. Access to paper website.

  8. Wang, C., Tan, Z., Niu, B., ... & Zhang, M. Q., Chan, D., Cheah K.S.E. (2018). Inhibiting the integrated stress response pathway prevents aberrant chondrocyte differentiation thereby alleviating chondrodysplasia. eLife, 7.


  9. Tan, Z., Niu, B. (co-first author),...Chan, D., Zhang, M. Q. & Cheah K.S.E. (2018). Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions. PLoS Genetics, 14(4), e1007346.

    Access to paper website.

  10. Liu, J. A., Rao, Y., Cheung, M. P. L., Hui, M. N., Wu, M. H., Chan, L. K., Ng I.O.L., Niu, B., Cheah K.S.E., Sharma R., Hodgson L. and Cheung M.C.H. (2017). Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration. Nature Communications, 8(1), 1185.

    11. Faculty Outstanding Research Output Award: Li Ka Shing Faculty of Medicine, The University of Hong Kong.

  11. Cheng, C. W., Niu, B. (co-first author), Warren, M., Pevny, L. H., Lovell-Badge, R., Hwa, T., & Cheah, K. S. (2014). Predicting the spatiotemporal dynamics of hair follicle patterns in the developing mouse. Proceedings of the National Academy of Sciences (PNAS), 111(7), 2596-2601.

    F1000Prime recommended by Professor Philip Maini, University of Oxford.

    The supplmentary material on proposed Computer model.

    Predicting the dynamic process of hair follicle patterning, results shown in movies.


  12. Niu, B., Yang, Q., Shiu, S. C. K., & Pal, S. K. (2008). Two-dimensional Laplacianfaces method for face recognition. Pattern Recognition, 41(10), 3237-3243.

  13. Yang, J., Zhang, D., Yang, J. Y., & Niu, B. (2007). Globally maximizing, locally minimizing: unsupervised discriminant projection with applications to face and palm biometrics. IEEE transactions on pattern analysis and machine intelligence (PAMI), 29(4), 650-664.

  14. Niu, B., Ha M.H., Wang X.Z. (2002). Design and implementation of a multi-agent system with fuzzy logic rules for parallel reasoning. Journal of Hebei University (Natural Science Edition), Issue 2, 2002.

  15. Niu, B., Ha M.H., Xizhao X.Z. (2002). Object-oriented Knowledge representation based on Visual C++ and Prolog. Journal of Hebei University of Science and Technology, Issue 1, 2002.


    16. Conference paper

  16. QIN, Y., Ng, R. K., Ng, T. W., Tong, K. K., Au, Y. K., Niu, B., ... & Cheah, K. S. E. (2017). Genome-wide identification of active enhancers in the developing mouse nucleus pulposus. In 2017 Hong Kong Inter-University Postgraduate Symposium in Biochemical Sciences.

  17. Szeto, Y. Y., Wu, M. H., Niu, B., & Cheah, K. S. E. (2017). Regulation of cell fate decision by microRNA in the mesendoderm lineage. GRC Germinal Stem Cells.

  18. Szeto, Y. Y., Wu, M. H., Niu, B., & Cheah, K. S. E. (2017). Regulation of cell fate decision by microRNA in the notochordal lineage. GRC Genome Architecture in Cell Fate and Disease.

  19. Au, Y. K., Cheah, K. S. E., Niu, B., Chan, D., & Zhang, M. Q. (2016). SPINE-GEL: a global gene expression library for the developing nucleus pulposus. SpineWeek 2016.

  20. Liu A.J., Ho S.H., Hui M.N., Cheung M.P.L., Wu M.H., Ho C.K.I., Niu, B., Cheah K.S.E. and Cheung M.C.H., Sox9-dependent pathway in regulating neural crest cell motility, Neural Crest & Cranial Placodes Gordon Research Conference Development, Malformations and Cancers. 2015. (Publication No. : 252701; Publication Date: Jul 2015)

  21. Cheah, K. S. E., Wang, C., Tan, Z., Niu, B., Tsang, K. Y., Melhado, I. G., ... & Chan, D. (2012). Transcriptional control of chondrocyte differentiation and their adaptation to ER stress in vivo. In CSHAsia 2012 Conference on Bone & Cartilage: from Development to Human Diseases.

  22. Niu, B., Tan, Z., Tsang, K. Y., Melhado, I. G., Chan, D., Zhang, M. Q., & Cheah, K. S. E. (2012). Bioinformatics-aided discovery of transcriptional regulators of chondrocyte differentiation in the growth plate. In Symposium of the Hong Kong Society for Developmental Biology, HKSDB 2012.

  23. Cheng, C. C. W., Niu, B., Lovell-Badge, R. H., Hwa, T. T., & Cheah, K. S. E. (2012). Predicting the establishment of hair follicle patterns in the developing mouse. In Symposium of the Hong Kong Society for Developmental Biology, HKSDB 2012.

  24. Tan, Z., Niu, B., Tsang, K. Y., Melhado, I. G., Zhang, M., Chan, D., & Cheah, K. S. E. (2011). Integration of factors and pathways facilitating chondrocyte adaptation to ER stress. GRC on Cartilage Biology & Pathology.

  25. Cheah, K. S. E., Wang, C., Tan, Z., Melhado, I. G., Niu, B., Tsang, K. Y., ... & Chan, D. (2010). Alleviating ER stress in chondrocytes: survival strategies with double-edged developmental consequences. In Annual Meeting of the Japanese Society of Developmental Biologists, JSDB-43.

  26. Cheah, K. S. E., Wang, C., Tan, Z., Niu, B., Tsang, K. Y., Melhado, I. G., ... & Zhang, M. (2010). Genetic and genomic analyses of chondrocyte adaptation to ER stress in vivo. In Meeting of the Federation of European Connective Tissue Societies, FECTS 2010.

  27. Cheah, K. S. E., Wang, C., Tan, Z., Melhado, I. G., Niu, B., Tsang, K. Y., ... & Chan, D. (2010). Genetic and genomic analyses of chondrocyte adaptation to ER stress. In Genetics Society 2010 Spring Meeting.

  28. Cheah, K. S. E., Tan, Z., Niu, B., Tsang, K. Y., Chan, D., Zhang, M., ... & Wang, C. (2010). Integration of pathways mediating chondrocyte adaptation to ER stress in VIVO. In CSHL Meeting on Mouse Development, Genetics & Genomics.

  29. Tan, Z., Niu, B., Tsang, K. Y., Melhado, I. G., Zhang, M., Chan, D., & Cheah, K. S. E. (2010). Global gene expression changes during chondrocyte adaptation to ER stress. In Hong Kong Inter-University 2010 Biochemistry Postgraduate Symposium.

  30. Tan, Z., Niu, B., Tsang, K. Y., Melhado, I. G., Chan, D., Cheah, K. S. E., & Zhang, M. (2010). Mechanistic insight into chondrocyte adaptation to ER stress. In Research Postgraduate Symposium, RPS 2010.

  31. Tan, Z., Niu, B., Chan, D., & Cheah, K. S. E. (2009). Mechanisms Underlying Chondrocyte Reprogramming Surviving ER Stress. In Research Postgraduate Symposium, RPS 2009.

  32. Niu, B., Wang, H., Ng, P. H., & Shiu, S. C. (2009, June). A neural-evolutionary model for case-based planning in real time strategy games. In International Conference on Industrial, Engineering and Other Applications of Applied Intelligent Systems (pp. 291-300). Springer, Berlin, Heidelberg.

  33. Huo, P., Shiu, S. C., Wang, H., & Niu, B. (2009, August). Application and comparison of particle swarm optimization and genetic algorithm in strategy defense game. In 2009 Fifth International Conference on Natural Computation (pp. 387-392). IEEE.

  34. Huo, P., Shiu, S. C. K., Wang, H., & Niu, B. (2009, December). Case indexing using PSO and ANN in real time strategy games. In International Conference on Pattern Recognition and Machine Intelligence (pp. 106-115). Springer, Berlin, Heidelberg.

  35. Wang, H., Ng, P. H., Niu, B., & Shiu, S. C. (2009, August). Case learning and indexing in real time strategy games. In Natural Computation, 2009. ICNC'09. Fifth International Conference (Vol. 1, pp. 100-104). IEEE.

  36. Niu, B., Shiu, S. C. K., & Pal, S. (2009, December). Mutual neighborhood based discriminant projection for face recognition. In International Conference on Pattern Recognition and Machine Intelligence (pp. 440-445). Springer, Berlin, Heidelberg.

  37. Cheng, C. C. W., Leung, K. K. H., Niu, B., Chan, N. S., & Cheah, K. S. E. (2008). Light coat and circling (LCC) and yellow submarine (YSB) mutants are Sox2 conditional null models during hair morphogenesis. In CSHL Meeting on Mouse Genetics & Genomics. Cold Spring Harbor Laboratory.

  38. Niu, B., N., Yang, Q., Li, J., Chi-keung, S., & Pal, S. (2007, December). Discovering patterns of DNA methylation: rule mining with rough sets and decision trees, and comethylation analysis. In International Conference on Pattern Recognition and Machine Intelligence (pp. 389-397). Springer, Berlin, Heidelberg.

  39. Niu, B., Yang, Q., Li, J., Xue, H., Shiu, S., Liu, H., & Pal, S. K. (2007). Pattern Detection and Co-methylation Analysis of Epigenetic Features in Human Embryonic Stem Cells. In International Conference on BioInformatics 2007.

  40. Niu, B., Shiu, S. C. K., & Pal, S. K. (2006, November). Two dimensional laplacianfaces method for face recognition. In International Conference on Rough Sets and Current Trends in Computing (pp. 852-861). Springer, Berlin, Heidelberg.

  41. Niu, B., & Shiu, S. C. (2005, September). Using similarity measure to enhance the robustness of web access prediction model. In International Conference on Knowledge-Based and Intelligent Information and Engineering Systems (pp. 107-111). Springer, Berlin, Heidelberg.

  42. Niu, B., Shiu, S. C. K., & Pal, S. K. (2005, December). A novel 3D face recognition algorithm using template based registration strategy and artificial neural networks. In International Conference on Pattern Recognition and Machine Intelligence (pp. 315-317). Springer, Berlin, Heidelberg.

    43. Editorship, Invited lectures and keynote speeches

  43. Liu A.J., RAO Y., Cheung M.P.L., Hui M.N., Wu M.H., Niu, B., Chan L.K., Cheah /K.S.E. and Cheung M.C.H., Coordinated action of Nedd9 and Dlc1 in neural crest motility, Proceedings of Avian Model Systems 9: A New Integrative Platform. 2016. (Publication No. : 259888; Publication Date: Mar 2016)

  44. Cheung M.C.H., HO S.H., Hui M.N., Wu M.H., Cheung M.P.L., Ho C.K.Y., Niu, B., Cheah K.S.E. and LIU A., Sox9 and the Molecular Network Regulating Neural Crest Cell Motility, 2014 International SOX Research Conference. 2014. (Publication No. : 234935; Publication Date: Sep 2014)

  45. Cheah K.S.E., Wang C., Tan Z., Niu, B., Tsang K.Y., Melhado I.G., Zhong M. and Chan D., Transcriptional control of chondrocyte differentiation and their adaptation to ER stress in vivo, Cold Spring Harbor Asia Meeting on " Bone and Cartilage: from Development to Human Diseases , Suzhou, China, 11-15 June, 2012. (Publication No. : 200583; Publication Date: Jun 2012)

  46. Cheah K.S.E., Wang C., Tan Z., Niu, B., Tsang K.Y., Melhado I.G., Zhang M.Q. and Chan D., Genetic control of chondrocyte adaptation to ER stress in chondrodysplasia , Hong Kong Society for Developmental Biology Symposium : From Embryology to Disease Mechanism, November 26-26, 2012. (Publication No. : 213072; Publication Date: Nov 2012)

Quote-fountin

Last updated April 2019